Programme

Sunday, 17 March

	Arrival and Registration of Scholars and Faculty
16:45-17:30	Opening Ceremony and Presentation of the School
20:00	Dinner

Monday, 18 March

9:00–9:45	Giorgio Carmignoto Introduction to glial cells
9:45-10:30	Richard Robitaille Excitability of astrocytes: calcium signal
10:30-11:00	Coffee break
11:00-11:45	Andrea Volterra Gliotransmission
11:45-12:45	Gian Michele Ratto Methods to study calcium signal in brain network in vivo
12:45-14:30	Lunch break
14:30-15:30	Richard Robitaille Methods to study calcium imaging
15:30-16:15	Alfonso Araque Specific tools for astrocyte stimulation
16:15-16:45	Coffee break
16:45-17:30	Frank Kirchhoff Genetic tools for glial research in vivo
17:30-18:15	Nathalie Rouach Astrocytes in brain energy metabolism
18:15-19:15	Debate preparation
20:00	Dinner

Tuesday, 19 March

9:00-9:45	Andrea Volterra TNFα-dependent gliotransmission: switching synaptic physiology to pathology
9:45-10:30	Richard Robitaille Glial Cells decode and regulate synaptic transmission at PNS
10:30-11:00	Coffee break
11:00-11:45	Giovanni Marsicano Different roles of astroglial CB1 receptors
11:45-12:45	Oral Presentations by Scholars Karen Carney Proteomic identification of astrocyte proteins involved in synaptic plasticity Ana Covelo Fernández Endocannabinoid signaling induces lateral long-term potentiation of transmitter release by stimulating gliotransmission Ricardo Gómez Frequency-dependent transformation of GABAergic inhibition into glutamatergic potentiation in astrocyte-neuron networks Michele Sessolo Intense firing activity in individual fast-spiking interneurons potentiate excitatory synaptic transmission to nearby fast-spiking interneurons Silvana Valtcheva Glutamate uptake operated by astrocytes shapes spike-timing dependent plasticity Jose Fernando Oliveira da Cruz The role of astroglial type 1 cannabinoid receptor in memory functions
12:45-14:30	Lunch break
14:30-15:30	Oral Presentations by Scholars Houssam Darabid Glial cells decipher synaptic competition at the mammalian neuromuscular junction Gael Quesseveur BDNF overexpression in hippocampal astrocytes elicits neurogenesis-dependent and -independent anxiolytic-like activity Ricardo Martín Herranz Endocannabinoid-mediated calcium elevations in astrocytes evoke glutamate-induced slow inward currents in medium spiny neurons from dorsolateral striatum Mykhailo Batiuk Molecular machinery underlying gliotransmission Ilaria Prada Astrocytes can modulate brain cell activities via release of extracellular microvesicles Riccardo Parra Tagging diseased astrocites by means of a fluorescent reporter for Cre recombinase
15:30-16:15	Alfonso Araque Astrocyte modulation of hippocampal plasticity
16:15-16:45	Coffee break
16:45-17:30	Nathalie Rouach Role of astroglial networks in synaptic transmission and plasticity
17:30-18:15	Babette Fuss Sodium-dependent glutamate transporters: a role beyond extracellular glutamate clearance
18:15-19:15	Alessandro Cometta LSFM: the new frontier of live imaging
20:00	Dinner

Wednesday, 20 March

9:00-9:45	Frank Pfrieger Neuron-glia interactions: models matter!
9:45-10:30	Frank Kirchhoff Neuron-glia interaction in the cerebellum in vivo
10:30-11:00	Coffee break
11:00-11:45	Vladimir Parpura Mechanisms of glutamate release from astrocytes
11:45-12:45	Oral Presentations by Scholars Aurélien Briens Astrocytic modulation of neuronal toxicity of tPA Marko Muhič Cytosolic glucose concentration in single astrocytes Rachel Waller Characterising the transcriptomic and proteomic profile of astrocytes in normal appearing white matter in multiple sclerosis João Filipe Oliveira Assessing cognitive function in an animal model of glial pathology Angela Gallo ADAR2-editing activity inhibits glioblastoma growth through the modulation of the CDC14B/Skp2/p21/p27 axis
12:45-14:15	Lunch break
14:15-24:00	Escursion to Ravenna Guided tours and dinner in Ravenna, followed by return to Bertinoro

Thursday, 21 March

9:00-9:45	Stéphane Oliet Methods to study synaptic physiology
9:45-10:30	Tommaso Fellin Astrocyte modulation of neuronal circuits in the somatosensory cortex in vivo
10:30-11:00	Coffee break
11:00-11:45	Stéphane Oliet Surface dynamics of astroglial glutamate transporter GLT-1
11:45-12:45	Oral Presentations by Scholars Lior Mayo B4galt6 controls astrocytes activation during chronic CNS inflammation Sivan Kanner The effect of malfunctioning DNA damage response (DDR) on neuronal-glial circuits Jennifer Iddings Effects of chronic hypertension on cortical astrocyte and parenchymal arteriole function: potential mechanisms for hypertension-induced impairments in functional hyperemia Dmitry Lim Amyloid beta deregulates astroglial mGluR5-mediated Ca²⁺ signaling via calcineurin and NF-κB Chenju Yi Role of glial connexins in Alzheimer's disease Lana Martina Osborn Disturbances in astrocytic modulation of synaptic efficacy in Alzheimer’s: combining molecular biology and electrophysiology in the APPswe/PS1dE9 mouse
12:45-14:30	Lunch break
14:30-15:30	Oral Presentations by Scholars Vered Kellner Effects of astrocyte activation on spontaneous and evoked activity of neocortical neurons in Alzheimer's Disease model mice in vivo Nicola Mattugini NGF regulates the expression of a number of microRNAs representing potential new mediators of neuronal differentiation, plasticity and neuroprotection Laura Librizzi Seizure induced brain-born inflammation and blood-brain barrier damage are counteracted by ANAKINRA in the isolated guinea pig brain preparation Iacopo Marcon Investigating the role of interneurons-astrocytes signalling during seizure propagation in a mouse model of Dravet syndrome Mahmood Amiri Astrocyte-neuron interaction as a mechanism responsible for generation of neural synchrony
15:30-16:00	Coffee break
16:00-16:45	Gian Michele Ratto Neurons and astrocytes: order and chaos in normal and epileptic brain
16:45-17:30	Giorgio Carmignoto Astrocytes in focal epilepsy
17:30-19:15	Debate preparation
20:00	Dinner

Friday, 22 March

9:00-9:45	Keith Murai Astrocytes in synapse formation and plasticity
9:45-10:30	Robert Zorec Vesicle trafficking in astrocytes
10:30-11:00	Coffee break
11:00-11:45	Vladimir Parpura Exocytosis in astrocytes: emphasis on single vesicle/molecule measurements
11:45-12:45	Oral Presentations by Scholars Roselin Rachel Klever Astrocyte functioning in relation to high extracellular K⁺ and cortical spreading depression in transgenic migraine mice Aurora Raquel Barros Barbosa Modulatory role of A1 and P2X7 purinoceptors on high-affinity GABA and glutamate transporters and its involvement in mesial temporal lobe epilepsy (MTLE) Federico Scala Glioma cells induce neuronal zinc accumulation leading to depolarizing GABA_A receptor-mediated currents Kim Dekermendjian Kir4.1 activators: a mechanism for normalizing glutamate and potassium homoeostasis during seizures? Carla Alvarez Ferradas Dysfunctional spontaneous astroglial Ca²⁺ waves upregulate the glutamatergic synaptic efficacy in kindled epileptic rats Stefanie Anders Induction of rapid astrocyte morphology changes by epileptiform activity in vitro
12:45-14:30	Lunch break
14:30-18:15	Debates [Coffee break will be held at a suitable time]
18:15-19:15	General discussion and concluding remarks
20:00	Closing dinner

Saturday, 23 March

Departure

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